个人简历

教育简历

• 1994.09-2001.06    东北林业大学                        本科、硕士

• 2001.09-2004.06    必赢242net                            博士生

工作简历

• 2004.09-2006.06    上海中医药大学                      博士后

• 2006.07-2008.08    必赢242net                            讲师

• 2008.09-2009.09    Florida Atlantic University         Postdoctor

• 2009.10-2014.01    必赢242net                            讲师

• 2014.01-至今       必赢242net                            副教授,硕导,博导

博士生导师/方向

• 环境健康、基于微流控的生物分析

硕士生导师/方向

• 环境健康、基于微流控的生物分析

学术兼职

• 中国毒理学会会员

人才培养

本科生课程：

• 《环境生物学》

研究生课程：

• 《环境生态学》

科学研究

主持和参与的主要项目：

• 国家自然基金地区科学基金项目，21966027，基于3D血睾微流控芯片的纳米二氧化钛生殖毒性分子机制研究，2020/01-2023/12，41万元，在研，合作主持

• 国家自然基金面上项目，21876031，应用多器官微流控芯片系统对致癌细颗粒物体内代谢机制的模拟研究，2019/01- 2022/12，77.6 万元，在研，主持

• 国家自然基金面上项目，21577020，基于转录组测序及微流控芯片技术的PM2.5诱导人细胞促癌信号通路分子机制研究，2016/01-2019/12，77.8万元，结题，主持

• 国家自然基金面上项目，21377027，PM2.5对微流控芯片模拟人呼吸及心血管系统的细胞毒性机制研究，2014/01-2017/12，82万元，结题，主持

• 国家自然基金青年项目，20907010，藻毒素降解关键酶的高通量筛选及降解机理研究，2010/01-2012/12，20万元，结题，主持

教研成果

代表性专著：

代表性论文：

• Lulu Zheng﹟, Yuwen Wang﹟, Yule Zhang, Yongfeng Fu, Zhijin Yang, Yan Fan, Zhen Sun, Mantong Zhao, Lijun Zhu, Bo Dai, Dong An, Dawei Zhang*, Sixiu Liu*, EGFR inhibitors regulate Ca2+ concentration and apoptosis after PM2.5 exposure based on a lung-mimic microfluidic system, Science of the Total Environment, 2020, 761: 143200.

• Xiaoxiao Duan﹟, Lulu Zheng﹟, Xinlian Zhang, Bo Wang, Mingming Xiao, Wang Zhao, Sixiu Liu*, Guodong Sui*, A Membrane-free Liver-Gut-on-Chip Platform for the Assessment on Dysregulated Mechanisms of Cholesterol and Bile Acid Metabolism Induced by PM2.5, ACS Sensors, 2020, 5: 3483-3492.

• Yuhan Yao, Xi Chen, Xinlian Zhang, Qi Liu, Jinhui Zhu, Wang Zhao, Sixiu Liu*, Guodong Sui*, Rapid Detection of Influenza Virus Subtypes Based on an Integrated Centrifugal Disc, ACS Sensors, 2020, 5: 1354-1362.

• Chunmei Ling, Hongmei An, Li Li, Jiaqi Wang, Tianjiao Lu, Haixia Wang, Yunhua Hu, Guanling Song*, and Sixiu Liu*, Genotoxicity Evaluation of Titanium Dioxide Nanoparticles In Vitro: a Systematic Review of the Literature and Meta-analysis, Biological Trace Element Research, 2020, https://doi.org/10.1007/s12011-020-02311-8.

• Lulu Zheng﹟, Heng Dong﹟, Wang Zhao, Xinlian Zhang, Xiaoxiao Duan, Hao Zhang, Sixiu Liu*, Guodong Sui*, An Air–Liquid Interface Organ-Level Lung Microfluidics Platform for Analysis on Molecular Mechanisms of Cytotoxicity Induced by Cancer-Causing Fine Particles, ACS Sensors, 2019, 4(4): 907-917.

• Heng Dong﹟, Lulu Zheng﹟, Xiaoxiao Duan, Wang Zhao, Jianmin Chen, Sixiu Liu*, Guodong Sui*, Cytotoxicity analysis of ambient fine particle in BEAS-2B cells on an air-liquid interface (ALI) microfluidics system, Science of The Total Environment, 2019, 677: 108-119.

• Xiaoxiao Duan﹟, Linlin Zhao﹟, Heng Dong﹟, Wang Zhao, Sixiu Liu*, Guodong Sui*, Microfluidic Immunoassay System for Rapid Detection and Semi-Quantitative Determination of a Potential Serum Biomarker Mesothelin, ACS Sensors, 2019, 4(11): 2952-2957.

• Lulu Zheng, Sixiu Liu*, Guoshun Zhuang, Jian Xu, Qi Liu, Xinlian Zhang, Congrui Deng, Wang Zhao, Tingna Liu, Yiqi Wang, Yuxiao Zhang, Jin Lin, Qiongzhen Wang, Guodong Sui*, Signal Transductions of BEAS-2B Cells in Response to Carcinogenic PM2.5 Exposure Based on a Microfluidic System, Analytical Chemistry, 2017, 89(10), 5413–5421.

• Yuxiao Zhang﹟, Lulu Zheng﹟, Jiang Tuo, Qi Liu, Zhixuan Xu, Xinlian Zhang, Sixiu Liu*, Guodong Sui*, Analysis of PM2.5-induced cytotoxicity in human HaCaT cells based on a microfluidic system, Toxicology in Vitro, 2017,43, 1–8.